Sato T
Department of Dermatology, Akita University School of Medicine.
Nihon Rinsho. 1994 Jan;52(1):170-3.
It is well recognized that liver cirrhosis may cause many characteristic skin changes. This paper deals with skin manifestations of liver cirrhosis, according to the pathological process. Portal hypertension may cause development of collateral circulation, including, visible varicose veins on the abdominal wall ("caput Medusae"). Hormonal disturbances, as the result of inability of the liver, are responsible for several vascular changes, such as, red palm, vascular spider and "paper money" skin, for gynecomastia and for loss of axillary and pubic hair. Nail changes, such as, clubbing, white nails, watch-glass deformity, flat nails and brittleness may be found in the patient with liver cirrhosis. Jaundice and melanosis are common. These skin changes are recognized as contributing to a diagnosis and estimating the stage of liver cirrhosis.
众所周知，肝硬化可能会导致许多特征性的皮肤变化。本文根据病理过程探讨肝硬化的皮肤表现。门静脉高压可能导致侧支循环的形成，包括腹壁上可见的静脉曲张（“海蛇头”）。肝脏功能不全导致的激素紊乱会引发多种血管变化，如肝掌、蜘蛛痣和“钱币状”皮肤，还会导致男性乳房发育以及腋毛和阴毛脱落。肝硬化患者可能会出现指甲变化，如杵状指、白甲、表玻璃样畸形、扁平甲和指甲变脆。黄疸和黑变病很常见。这些皮肤变化有助于肝硬化的诊断和分期评估。
