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经支气管肺活检确诊的肺嗜酸性肉芽肿一例

[A case of pulmonary eosinophilic granuloma confirmed by transbronchial lung biopsy].

作者信息

Yagi T, Suzuki K, Yamagishi F, Sasaki Y, Miyazawa H, Ihara S, Nakano H, Kawabata Y

机构信息

Division of Thoracic Disease, National Chiba-Higashi Hospital, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Jan;32(1):111-5.

PMID:8114367
Abstract

A case of pulmonary eosinophilic granuloma confirmed by transbronchial lung biopsy (TBLB) is reported. A 63-year-old man was admitted to our hospital complaining of productive cough and exertional dyspnea. Chest roentgenogram and computed tomography showed bilateral linear and reticular shadows predominantly in the upper and middle lung fields. TBLB was performed and the specimens showed granulomatous lesions consisting of histiocytes with infiltration of eosinophils. Histiocytes were positive for S-100 protein by immunohistochemistry. He was diagnosed as having pulmonary eosinophilic granuloma. In the diagnosis of pulmonary eosinophilic granuloma, open lung biopsy is useful, but TBLB is also useful for diagnosis in the active or early stage of this disease.

摘要

报告1例经支气管肺活检(TBLB)确诊的肺嗜酸性肉芽肿病例。一名63岁男性因咳嗽咳痰和劳力性呼吸困难入院。胸部X线片和计算机断层扫描显示双侧以中上肺野为主的线状和网状阴影。进行了TBLB,标本显示由组织细胞组成的肉芽肿性病变,伴有嗜酸性粒细胞浸润。免疫组织化学显示组织细胞S-100蛋白呈阳性。他被诊断为肺嗜酸性肉芽肿。在肺嗜酸性肉芽肿的诊断中,开胸肺活检是有用的,但TBLB对本病的活动期或早期诊断也很有用。

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[A case of pulmonary eosinophilic granuloma diagnosed by TBLB].
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