Rohrschneider K, Schatanek S, Kruse F E, Sahl H, Völcker H E
Augenklinik Universität Heidelberg.
Klin Monbl Augenheilkd. 1993 Oct;203(4):275-8. doi: 10.1055/s-2008-1045680.
Choroidal Osteoma is a rare, typically monolateral benign ossifying tumor of the choroid found in healthy females aged 10 to 30 years. In contrast, multiple idiopathic sclerochoroidal calcifications occur in elderly otherwise healthy subjects. Local or generalized distortions of calcium phosphate metabolism may cause secondary choroidal calcifications.
We report on a 56-year-old woman, who underwent removal of a histologically verified osteoma 2 years ago. Ophthalmoscopically, there were multiple prominent choroidal tumors in the inferior midperiphery of both eyes. Ultrasonography showed high reflectivity and marked shadowing posterior to the lesion. CT-scan demonstrated the presence of calcifications. The patient neither belonged to the age group, in which choroidal osteomas are typically found, nor were the lesions located in the typical manner as reported in literature. The location in the inferior choroid has not yet been described for idiopathic sclerochoroidal calcifications. The presence of secondary choroidal calcifications was very unlikely, as there was no history of ocular inflammation or systemic disease such as hyperparathyreoidism or chronic renal failure.
Thus, despite the lack of histologic examination, one may assume the rare incidence of bilateral choroidal osteomas in atypical inferior localisation in our patient.
脉络膜骨瘤是一种罕见的、通常为单侧的脉络膜良性骨化肿瘤，多见于10至30岁的健康女性。相比之下，多发性特发性巩膜脉络膜钙化发生于其他方面健康的老年人。磷酸钙代谢的局部或全身性紊乱可能导致继发性脉络膜钙化。
我们报告一例56岁女性，她在2年前接受了组织学证实的骨瘤切除手术。眼底镜检查发现双眼下中周边部有多个明显的脉络膜肿瘤。超声检查显示病变后方有高反射性和明显的声影。CT扫描显示有钙化。该患者既不属于脉络膜骨瘤通常出现的年龄组，病变的位置也不像文献报道的那样典型。特发性巩膜脉络膜钙化尚未有位于脉络膜下部的报道。由于没有眼部炎症或系统性疾病（如甲状旁腺功能亢进或慢性肾衰竭）的病史，继发性脉络膜钙化的可能性非常小。
因此，尽管缺乏组织学检查，但我们可以推测该患者双侧脉络膜骨瘤罕见地发生于非典型的下部位置。
