Rakich P M, Latimer K S, Mispagel M E, Steffens W L
Athens Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia.
Vet Pathol. 1993 Nov;30(6):555-9. doi: 10.1177/030098589303000609.
Four adult dogs received experimentally controlled stings in the dorsolateral abdominal skin by imported fire ants (Solenopsis invicta). The sites were examined grossly 15 minutes and at 1, 2, 3, 4, 5, 6, 24, 48, and 72 hours and histologically 15 minutes and 6, 24, 48, and 72 hours after stinging. The initial gross lesions at 15 minutes were swelling and erythema, and the microscopic changes were vascular congestion and superficial dermal edema. By 6 hours, the lesions consisted of bright erythematous pruritic papules characterized microscopically by a band of full thickness dermal necrosis and inflammation. By 24 hours and continuing to the end of the study at 72 hours, the sites appeared completely normal grossly. Biopsies taken 24, 48, and 72 hours after stings contained microscopic changes similar to those present at 6 hours after stings. These histologic changes are unlike those described for human beings stung by imported fire ants. In human beings, fire ant stings are characterized histologically by an initial superficial vesicle that evolves into a sterile pustule.
四只成年犬在实验控制下，其腹部背外侧皮肤被入侵红火蚁（Solenopsis invicta）蜇刺。在蜇刺后15分钟、1、2、3、4、5、6、24、48和72小时对蜇刺部位进行大体检查，并在蜇刺后15分钟、6、24、48和72小时进行组织学检查。15分钟时最初的大体病变为肿胀和红斑，显微镜下变化为血管充血和真皮浅层水肿。到6小时时，病变表现为鲜红色瘙痒性丘疹，显微镜下特征为全层真皮坏死和炎症带。到24小时时，病变部位大体上看起来完全正常，并一直持续到研究结束的72小时。在蜇刺后24、48和72小时取的活检组织中，显微镜下变化与蜇刺后6小时时相似。这些组织学变化与被入侵红火蚁蜇刺的人类所描述的变化不同。在人类中，火蚁蜇刺在组织学上的特征是最初出现一个浅表水疱，随后发展为无菌脓疱。
