Mulier T, Morgan M, Fabry G
Department of Orthopaedic Surgery, Katholieke Universiteit Leuven, Pellenberg, Belgium.
Acta Orthop Belg. 1993;59(4):416-9.
One of the basic principles of orthopedic surgery is that gas gangrene does not develop in closed fractures. That there are exceptions to this rule is demonstrated by the following report of an extremely rare case. Clostridium septicum myonecrosis developed after surgical treatment of a closed femoral fracture in a fit 45-year-old man, treated by antibiotics. The patient survived after having a right hip disarticulation and administration of high doses of intravenous penicillin. Prophylactically administered cephalosporins failed to prevent the Clostridial infection.
矫形外科的基本原则之一是气性坏疽不会在闭合性骨折中发生。以下这份关于一个极其罕见病例的报告表明，这条规则存在例外情况。一名45岁健康男性因闭合性股骨骨折接受手术治疗并使用了抗生素，之后发生了败血梭菌性肌坏死。该患者在接受右髋关节离断术并大剂量静脉注射青霉素后存活下来。预防性使用的头孢菌素未能预防梭菌感染。
