Jamison J P, Ivey F M
University of Texas Medical Branch, Galveston.
Orthop Rev. 1986 Oct;15(10):658-63.
Physicians are aware of the association between massively contaminated wounds and clostridial myonecrosis, or gas gangrene. A far less common but equally devastating presentation is that of nontraumatic or spontaneous gas gangrene. The most frequently encountered organism in this rare form of gangrene is Clostridium septicum, and there is a high correlation with hematologic or gastrointestinal malignancy. The mainstays of treatment are intravenous antibiotics, surgical debridement, and hyperbaric oxygen therapy. The prognosis is dependent upon early recognition and institution of treatment.
医生们都知道，伤口大量污染与梭菌性肌坏死或气性坏疽之间存在关联。一种远不那么常见但同样具有毁灭性的表现是非创伤性或自发性气性坏疽。在这种罕见的坏疽形式中最常遇到的病原体是败血梭菌，并且与血液系统或胃肠道恶性肿瘤高度相关。治疗的主要方法是静脉注射抗生素、手术清创和高压氧治疗。预后取决于早期识别和治疗的开展。
