Uno Y, Momoi Y, Watari T, Goitsuka R, Tsujimoto H, Shimada T, Ono K, Goto N, Hasegawa A
Department of Veterinary Internal Medicine, Faculty of Agriculture, University of Tokyo, Japan.
J Vet Med Sci. 1993 Dec;55(6):1059-61. doi: 10.1292/jvms.55.1059.
A 7-year-old male Yorkshire terrier was examined for multiple plaques and nodules on the skin. The clinical, cytological and histopathological features indicated a malignant histiocytosis. Cytoreductive chemotherapy produced moderate clinical improvement, but died at day 90 after the first admission. Pathological examination revealed the neoplastic histiocytes in the skin as well as in the myocardium and skeletal muscles.
一只7岁雄性约克夏梗因皮肤出现多处斑块和结节接受检查。临床、细胞学和组织病理学特征表明为恶性组织细胞增生症。减瘤化疗使临床症状有中度改善，但在首次入院后第90天死亡。病理检查发现皮肤、心肌和骨骼肌中均有肿瘤性组织细胞。
