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神经性厌食症中对联合药物和心理治疗方案抵抗的因素。综述。

Elements of resistance to a combined medical and psychotherapeutic program in anorexia nervosa. An overview.

作者信息

Pierloot R A, Wellens W, Houben M E

出版信息

Psychother Psychosom. 1975;26(2):101-17. doi: 10.1159/000286917.

Abstract

According to several follow-up studies in the literature, anorexia nervosa has to be considered as an affection with a grave prognosis. We have studied the outcome in a group of 32 female patients who could be considered as homogeneous in a number of aspects. The following five criteria, on which the delineation of the syndrome is based, were realized in all the patients: considerable weight loss; limited food intake; amenorrhea; juvenile age of onset; absence of primary organic or specific psychotic disorder. All of them presented a serious symptomatology and had undergone some previous treatment under the form of ambulatory psychotherapy and/or forced feeding. They all received, during their admission in the same hospital, the same form of combined intensive medical and psychotherapeutic treatment. All of them maintained regular psychotherapeutic contacts with the same psychiatrist. According to the outcome, the patients could be categorized into three groups: the cured, the improved, the unimproved. In order to circumscribe some prognostic elements, we have compared a number of clinical, family and personality variables in these groups. As favorable clinical factors can be mentioned: younger age at admission and shorter duration of the illness. Manifestations of impulsive behavior (automutilation, kleptomania, fugues, etc. ...) and sucide attempts are unfavorable. No definite family factors can be defined, although the absence of psychological interaction with the father seems to be unfavorable. A better prognostic outcome is offered by the following personality characteristics, determined by psychological testing: lower neuroticism and higher self-defensiveness on the ABV; a lower general profile and especially a lower score on the schizophrenia scale of the MMPI; less pronounced tendencies to infantile regression, passivity and sexual repression as these are expressed in the TAT.

摘要

根据文献中的多项随访研究,神经性厌食症必须被视为一种预后严重的疾病。我们研究了一组32名女性患者的预后情况,这些患者在多个方面可被视为具有同质性。所有患者均符合以下五项作为该综合征界定基础的标准:体重显著减轻;食物摄入量有限;闭经;发病年龄为青少年;无原发性器质性或特定精神障碍。她们均表现出严重的症状,并且之前都接受过某种形式的门诊心理治疗和/或强制喂食。她们在同一家医院住院期间,均接受了相同形式的综合强化药物和心理治疗。她们都与同一位精神科医生保持定期的心理治疗联系。根据预后情况,患者可分为三组:治愈组、改善组、未改善组。为了确定一些预后因素,我们比较了这些组中的一些临床、家庭和个性变量。可提及的有利临床因素有:入院时年龄较小和病程较短。冲动行为(自我伤害、盗窃癖、神游等)和自杀未遂的表现则不利。虽然与父亲缺乏心理互动似乎不利,但尚无明确的家庭因素可确定。通过心理测试确定的以下个性特征预示着更好的预后:ABV上较低的神经质和较高的自我防御性;MMPI中较低的总体概况,尤其是在精神分裂症量表上较低的得分;在TAT中表现出的婴儿期退行、被动和性压抑倾向不那么明显。

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