rum1 +基因对细胞周期G1期进程的调控。
Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene.
作者信息
Moreno S, Nurse P
机构信息
Department of Biochemistry, Oxford University, London, UK.
出版信息
Nature. 1994 Jan 20;367(6460):236-42. doi: 10.1038/367236a0.
DOI:10.1038/367236a0
PMID:8121488
Abstract
The rum1+ gene is identified as a new regulator of G1 progression in fission yeast. It influences three aspects of G1 regulation: determination of the length of G1, dependence of S phase upon completion of mitosis, and restraint of mitosis until G1 is finished. We propose that it has a central role in regulating the G1 phase of the cell cycle.
摘要
rum1+基因被鉴定为裂殖酵母中G1期进程的一种新调节因子。它影响G1调节的三个方面：G1期长度的确定、S期对有丝分裂完成的依赖性以及有丝分裂的抑制直至G1期结束。我们认为它在调节细胞周期的G1期方面具有核心作用。
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