Peachey N S, Goto Y, al-Ubaidi M R, Naash M I
VA Hospital, Hines, IL 60141.
Neurosci Lett. 1993 Nov 12;162(1-2):9-11. doi: 10.1016/0304-3940(93)90547-x.
Cone-mediated electroretinograms (ERGs) were obtained from normal mice during the course of light adaptation to a rod-desensitizing adapting field. Responses obtained during the early minutes of light adaptation were smaller in amplitude, and delayed in implicit time in comparison to responses obtained to the same stimulus presented later during light adaptation. These changes resemble those observed in the human cone ERG obtained under similar stimulus conditions, and indicate that the underlying mechanism may be similar. While the use of an adapting field appears to isolate the mouse cone ERG, these adaptation-induced changes should be considered when evaluating this response.
在正常小鼠对杆细胞脱敏适应场进行光适应的过程中，获得了视锥介导的视网膜电图（ERG）。与光适应后期对相同刺激所获得的反应相比，光适应早期获得的反应幅度较小，且潜伏期延迟。这些变化类似于在类似刺激条件下获得的人类视锥ERG中观察到的变化，表明其潜在机制可能相似。虽然使用适应场似乎可以分离小鼠视锥ERG，但在评估这种反应时应考虑这些适应诱导的变化。
