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[人工髋关节假体植入人体后,对等离子喷涂羟基磷灰石涂层假体与骨界面的组织学分析]

[Histological analysis of the bone/prosthesis interface in man after implantation of a hip prosthesis coated with plasma-sprayed hydroxyapatite].

作者信息

Frayssinet P, Hardy D, Conte P, Delince P, Guilhem A, Bonel G

机构信息

Bioland, Service de Génie biologique, Toulouse.

出版信息

Rev Chir Orthop Reparatrice Appar Mot. 1993;79(3):177-84.

PMID:8122005
Abstract

Thin coatings of calcium phosphate hydroxyapatite on metal alloys provide to these materials biological properties of calcium phosphates. We have analysed, using histological techniques or newly developed scanning electronic microscopy techniques, hip prostheses implanted into humans for periods from a few days up to twenty six months. The results of these analyses confirm the good osteointegration of these prostheses observed during clinical studies. Moreover, an active remodeling of the bone in contact with the ceramic-coating was observed. The coating was also concerned by the remodeling process and evolved once implanted.

摘要

金属合金上的磷酸钙羟基磷灰石薄涂层赋予这些材料磷酸钙的生物学特性。我们使用组织学技术或新开发的扫描电子显微镜技术,分析了植入人体几天至26个月不等的髋关节假体。这些分析结果证实了临床研究中观察到的这些假体良好的骨整合情况。此外,还观察到与陶瓷涂层接触的骨有活跃的重塑过程。涂层也参与了重塑过程,植入后会发生演变。

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