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[儿茶酚胺对山羊葡萄糖、脂肪酸代谢及心率的影响]

[Effect of catecholamines on the metabolism of glucose, fatty acids and on the heart rate in goats].

作者信息

Bartos S, Dolezel F, Kölbl M

出版信息

Vet Med (Praha). 1975 May;20(5):289-301.

PMID:812243
Abstract

In goats of the Bohemian white breed the effects of increasing doses of adrenaline and noradrenaline on the changes of glycemia, the NEFA level in the plasma, and on changes of the cardiac frequency were investigated. The reaction of the cardiac frequency to i. v. applications of adrenaline and noradrenaline corresponded, as a matter of fact to the reaction observed in monogastric animals. Between adrenaline doses of 6.25 and 12.5 mug kg(-1) no conclusive difference was recorded in the effect on an increase of glycemia. Only in the case of the application of adrenaline in a dose of 25.0 mu kg(-1) there occurred a conclusively higher response of glycemia compared with the lower doses. In the case of noradrenaline no dependence on concentration was recorded in the glycemic response. Between the applied dose of both catecholamines and the increased NEFA level no dependence on concentration was observed. No interaction between the acting of adrenaline and insulin was recorded. The results obtained indicate that adrenaline and insulin affect the cardiac frequency and the level of glycemia independently from each other.

摘要

在波希米亚白山羊品种中,研究了递增剂量的肾上腺素和去甲肾上腺素对血糖变化、血浆中游离脂肪酸(NEFA)水平以及心率变化的影响。实际上,心率对静脉注射肾上腺素和去甲肾上腺素的反应与在单胃动物中观察到的反应一致。在肾上腺素剂量为6.25至12.5微克/千克(-1)之间,对血糖升高的影响未记录到决定性差异。仅在应用25.0微克/千克(-1)剂量的肾上腺素时,与较低剂量相比,血糖出现了明显更高的反应。就去甲肾上腺素而言,未记录到血糖反应对浓度的依赖性。在所应用的两种儿茶酚胺剂量与升高的NEFA水平之间,未观察到对浓度的依赖性。未记录到肾上腺素和胰岛素作用之间的相互作用。所获得的结果表明,肾上腺素和胰岛素彼此独立地影响心率和血糖水平。

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