Prömpeler H J, Madjar H, Klosa W, du Bois A, Zahradnik H P, Schillinger H, Breckwoldt M
Department of Obstetrics and Gynecology, University of Freiburg, Germany.
Acta Obstet Gynecol Scand. 1994 Mar;73(3):205-8. doi: 10.3109/00016349409023440.
Analysis of the fetal outcome of the surviving twin and the cause of fetal death.
Between January 1979 and December 1992, 43 twin pregnancies with single fetal death were observed: in 11 cases (group I) before 16 weeks of gestation, in 11 cases (group II) between 17 and 24 weeks, and in 21 cases (group III) after 24 weeks of gestation.
The pregnancies in group I continued without complication. In groups II and III the incidence of preterm delivery was 50%, of cesarean section 59%, of growth retardation of the surviving twin 22% and perinatal mortality was 13%. Twenty-five (78%) of the surviving twins had a normal postnatal development and one (3%) was handicapped.
Loss of one of the twins in the first trimester does not impair the development of the surviving fetus. In the second trimester however this even is associated with increased risk for the survivor as reflected by a high incidence of growth retardation, premature labor and perinatal mortality.
分析存活双胎之一的胎儿结局及胎儿死亡原因。
1979年1月至1992年12月期间，观察到43例单胎死亡的双胎妊娠：11例（I组）发生在妊娠16周前，11例（II组）发生在17至24周之间，21例（III组）发生在妊娠24周后。
I组妊娠持续且无并发症。II组和III组早产发生率为50%，剖宫产率为59%，存活双胎生长受限发生率为22%，围产儿死亡率为13%。25例（78%）存活双胎出生后发育正常，1例（3%）有残疾。
孕早期双胎之一死亡不影响存活胎儿的发育。然而，孕中期这种情况会使存活胎儿风险增加，表现为生长受限、早产和围产儿死亡率高发。
