乙琥胺诱发的狼疮-硬皮病综合征。

Arch Dis Child. 1975 Aug;50(8):658-61. doi: 10.1136/adc.50.8.658.

Features of both systemic lupus erythematosus and scleroderma developed in a young Chinese girl while on multiple anticonvulsant therapy. These were reversed after withdrawal of the drugs. Readministration of ethosuximide for control of epilepsy caused a relapse with predominant sclerodermatous features. These clinical signs again resolved after ethosuximide withdrawal.

一名年轻中国女孩在接受多种抗惊厥药物治疗期间出现了系统性红斑狼疮和硬皮病的特征。停药后这些症状得到缓解。再次给予乙琥胺控制癫痫发作导致病情复发，主要表现为硬皮病特征。停用乙琥胺后这些临床症状再次消失。