脯氨酸在二肽诱导的四膜虫印记形成中的作用。在激素进化中的可能作用。
Role of proline in the imprinting developed by dipeptides--in Tetrahymena. Possible role in hormone evolution.
作者信息
Csaba G, Kovács P
机构信息
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
出版信息
Experientia. 1994 Feb 15;50(2):107-9. doi: 10.1007/BF01984944.
The effects of proline and serine dipeptides containing phenylalanine, alanine and leucine on the behaviour of receptors of Tetrahymena were investigated. Only proline-containing dipeptides were able to develop positive imprinting, and the activity depended on which other amino acid was present in the dipeptide. In contrast to the positive imprinting effect of the dipeptides Pro-Phe and Pro-Ala, the dipeptide Pro-Pro and Pro-Leu caused negative imprinting. Serine dipeptides produced negative imprinting in all cases. The possible importance of proline in the evolution of hormone specificity is discussed.
研究了含有苯丙氨酸、丙氨酸和亮氨酸的脯氨酸和丝氨酸二肽对四膜虫受体行为的影响。只有含脯氨酸的二肽能够产生正向印记，且活性取决于二肽中存在的其他氨基酸。与二肽Pro-Phe和Pro-Ala的正向印记效应相反，二肽Pro-Pro和Pro-Leu引起负向印记。丝氨酸二肽在所有情况下均产生负向印记。讨论了脯氨酸在激素特异性进化中的可能重要性。
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