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[无法治愈的细菌性皮肤感染]

[Incurable bacterial skin infection].

作者信息

Nishijima S, Namura S, Kawai S

机构信息

Department of Dermatology, Kansai Medical University.

出版信息

Nihon Rinsho. 1994 Feb;52(2):479-84.

PMID:8126906
Abstract

The most dominant species isolated from bacterial skin infection is always Staphylococcus aureus (S. aureus). The frequency of isolation of methicillin resistant S. aureus (MRSA) has recently been increasing in skin infections. MRSA is resistant to many kinds of antibiotics, therefore, MRSA infections is incurable, in many cases. MRSA are isolated most often from infectious decubitus or leg ulcers, in compromised hosts. S. aureus is etiologically related to atopic dermatitis. Simultaneously with S. aureus, there is a increasing frequency of isolation of Streptococcus pyogenes (S. pyogenes) in atopic dermatitis. S. pyogenes infections are much more severe because patients infected with S. pyogenes have fever and/or concurrent kidney disorders. In these skin disorders, there is severe skin damage or defect, so that, it may be very difficult to eradicate MRSA in decubitus, ulcers and S. pyogenes in atopic dermatitis.

摘要

从细菌性皮肤感染中分离出的最主要菌种一直是金黄色葡萄球菌(金葡菌)。耐甲氧西林金葡菌(MRSA)在皮肤感染中的分离频率近来一直在上升。MRSA对多种抗生素耐药,因此,在很多情况下,MRSA感染无法治愈。在免疫功能低下的宿主中,最常从感染性褥疮或腿部溃疡中分离出MRSA。金葡菌在病因上与特应性皮炎有关。与金葡菌同时出现的是,特应性皮炎中化脓性链球菌(化脓性链球菌)的分离频率也在增加。化脓性链球菌感染要严重得多,因为感染化脓性链球菌的患者会发烧和/或并发肾脏疾病。在这些皮肤疾病中,存在严重的皮肤损伤或缺损,因此,要根除褥疮中的MRSA以及特应性皮炎中的化脓性链球菌可能非常困难。

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