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[创伤后急性呼吸窘迫综合征——肺移植的潜在指征?]

[Post-traumatic ARDS--a potential indication for lung transplantation?].

作者信息

Demertzis S, Haverich A

机构信息

Klinik für Thorax-, Herz- und Gefässchirurgie, Medizinische Hochschule Hannover.

出版信息

Unfallchirurg. 1993 Dec;96(12):615-7.

PMID:8128253
Abstract

Posttraumatic adult respiratory distress syndrome (ARDS) still involves significant mortality, despite progress in management concepts. Current therapeutic strategies are briefly described, including kinetic therapy, high-frequency jet ventilation and extracorporeal membrane oxygenation. In addition, a spectacular case of the first successful lung transplantation for posttraumatic ARDS after failed ECMO (extracorporeal membrane oxygenation) support is reported. This young man with severe posttraumatic ARDS developed a potentially lethal bilateral pulmonary hemorrhage under treatment with ECMO, and on the basis of this bilateral pulmonary transplantation was considered to be indicated. The patient is alive and well 2 years after the procedure.

摘要

尽管在管理理念上取得了进展,但创伤后成人呼吸窘迫综合征(ARDS)的死亡率仍然很高。本文简要介绍了当前的治疗策略,包括动态治疗、高频喷射通气和体外膜肺氧合。此外,还报告了一例在体外膜肺氧合(ECMO)支持失败后首次成功进行创伤后ARDS肺移植的显著病例。这名患有严重创伤后ARDS的年轻人在接受ECMO治疗时出现了潜在致命的双侧肺出血,基于此,双侧肺移植被认为是必要的。该患者在手术后两年仍然健在。

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