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[骨移植中的HIV筛查]

[HIV-screening in bone transplantation].

作者信息

Bettin D, Dethloff M, Polster J, Steinbeck J, Fiedler R

机构信息

Orthopädische Klinik Münster.

出版信息

Unfallchirurg. 1993 Dec;96(12):636-40.

PMID:8128258
Abstract

Tissue transplantation obviously always involves the risk of HIV transmission. Since 1980, the Orthopaedic University of Muenster has conducted careful anamnestic and laboratory screening in 62 donors. Epidemiological investigations show that 90.1% of HIV-positive people in Germany are between 20 and 50 years old. For 25 donors (40%) the results of the HIV antigen test performed in the recipients of the other organs guaranteed HIV negativity. A further 17 donors (28%) were outside the epidemiologic risk group aged between 20 and 50 years. Tissue from all 20 other donors (32%) was subjected to a secondary sterilization method, e.g. fumigation with ethylene oxide or irradiation with 25 kGy.

摘要

组织移植显然始终存在艾滋病毒传播的风险。自1980年以来,明斯特骨科大学对62名捐赠者进行了仔细的既往史询问和实验室筛查。流行病学调查显示,德国90.1%的艾滋病毒阳性者年龄在20至50岁之间。对于25名捐赠者(40%),在其他器官接受者中进行的艾滋病毒抗原检测结果保证其艾滋病毒呈阴性。另有17名捐赠者(28%)不在20至50岁的流行病学风险组内。来自其他所有20名捐赠者(32%)的组织都采用了二次灭菌方法,如环氧乙烷熏蒸或25千戈瑞的辐照。

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