Nyerges G, Telegdy L
Infection. 1975;3(4):213-6. doi: 10.1007/BF01642768.
Leukocyte migration inhibition /LMI/ tests were carried out in 19 patients with Brucella abortus bovis infection and in 18 healthy control subjects using killed Brucella abortus bovis as antigen. In the brucellosis group a statistically significant LMI was observed, as compared to the members of the control group. Using the same antigen, a fairly good correlation was found between the local skin reaction and the results of the LMI test in the subacute or chronic stage of the disease. However, the results of the LMI test showed no correlation with either the clinical activity of the disease or the serological results and the general reactions elicited by the skin test. Since LMI and skin tests give nearly identical results in subacute or chronic brucellosis, it is suggested that the LMI test may be used as a safe test instead of the skin test.
以牛种布鲁氏菌作为抗原，对19例牛种布鲁氏菌感染患者及18名健康对照者进行了白细胞游走抑制（LMI）试验。与对照组相比，布鲁氏菌病组观察到具有统计学意义的白细胞游走抑制现象。使用相同抗原，发现在疾病的亚急性或慢性阶段，局部皮肤反应与白细胞游走抑制试验结果之间存在相当良好的相关性。然而，白细胞游走抑制试验结果与疾病的临床活动、血清学结果以及皮肤试验引发的全身反应均无相关性。由于在亚急性或慢性布鲁氏菌病中白细胞游走抑制试验和皮肤试验结果几乎相同，因此建议白细胞游走抑制试验可作为一种安全的试验替代皮肤试验。
