糖尿病患者的空腹生长激素水平。

Fasting growth hormone levels in diabetes mellitus.

作者信息

Nazaimoon W M, Ng M L, Khalid B A

机构信息

Departments of Biochemistry & Medicine, Universiti Kebangsaan Malaysia.

出版信息

Ann Acad Med Singap. 1993 Nov;22(6):861-3.

PMID:8129344

Abstract

Fasting serum growth hormone (GH) levels of different groups of diabetic patients were measured and compared to age-matched normal subjects. Insulin-dependent diabetes mellitus (IDDM) children (aged 12-17 years) were found to have significantly lower fasting GH levels than age-matched normal children (p < 0.001). In the adult age groups of 18-44 and 45-76 years, the IDDM patients showed increased fasting GH levels compared to age-matched normal subjects (p < 0.06 and p < 0.001 respectively) and non-insulin-dependent diabetes mellitus (NIDDM) patients (p < 0.05 and p < 0.001 respectively). The fasting GH levels of IDDM patients of the age group 18-44 years also showed significant correlations with glycated haemoglobin (r = 0.510, p = 0.002) and fasting blood sugar levels (r = 0.571, p = 0.01).

摘要

测量了不同组糖尿病患者的空腹血清生长激素（GH）水平，并与年龄匹配的正常受试者进行比较。发现胰岛素依赖型糖尿病（IDDM）儿童（12 - 17岁）的空腹GH水平显著低于年龄匹配的正常儿童（p < 0.001）。在18 - 44岁和45 - 76岁的成年年龄组中，与年龄匹配的正常受试者相比，IDDM患者的空腹GH水平升高（分别为p < 0.06和p < 0.001），与非胰岛素依赖型糖尿病（NIDDM）患者相比也升高（分别为p < 0.05和p < 0.001）。18 - 44岁年龄组的IDDM患者空腹GH水平还与糖化血红蛋白显著相关（r = 0.510，p = 0.002）以及空腹血糖水平显著相关（r = 0.571，p = 0.01）。