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[顺铂、5-氟尿嘧啶与香菇多糖联合用于胃癌伴腹膜播散的术后免疫化疗效果]

[Postoperative immunochemotherapy for gastric carcinoma with peritoneal dissemination--the effects with the combination of CDDP, 5-FU and lentinan].

作者信息

Mio H, Terabe K

机构信息

Dept. of Surgery, Shinshiro Municipal Hospital.

出版信息

Gan To Kagaku Ryoho. 1994 Mar;21(4):531-4.

PMID:8129395
Abstract

Three cases of postoperative gastric cancer with peritoneal dissemination were treated by combined administration of CDDP, 5-FU and Lentinan. CDDP was given intravenously at 20 mg/body on days one to five. At the same time, 5-FU was infused continuously 250-500 mg/body per day for more than two weeks, and Lentinan was given at a dose of 2 mg per week. Two courses were repeated every 3 weeks. This combination treatment was very effective because the median survival rate for the three patients was 13 months with no sign of recurrence, and the quality of life has been good.

摘要

三例术后胃癌伴腹膜播散患者接受了顺铂、5-氟尿嘧啶和香菇多糖联合治疗。顺铂于第1至5天静脉注射,剂量为20mg/体。同时,5-氟尿嘧啶每天持续输注250 - 500mg/体,持续两周以上,香菇多糖每周给药剂量为2mg。每3周重复两个疗程。这种联合治疗非常有效,因为这三名患者的中位生存期为13个月,无复发迹象,生活质量良好。

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A combination immunochemotherapy of 5-fluorouracil, cisplatin, leucovorin, and OK-432 for advanced and recurrent gastric carcinoma.5-氟尿嘧啶、顺铂、亚叶酸钙和OK-432联合免疫化疗用于晚期和复发性胃癌的治疗。
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