Chirossel P, Erpeldinger S, Sroussi J C, Froment A, Amiel M
Laboratoire d'explorations fonctionnelles vasculaires, Hôpital cardiologique, Lyon.
Arch Mal Coeur Vaiss. 1993 Aug;86(8):1237-40.
The purpose of the study is a rigorous validation of different ultrasonic criteria of renal artery stenosis, and the presentation of the performances of duplex sonography in renal artery stenosis screening. Sixty seven patients have been investigated by ultrasonic techniques, and the results of duplex compared with intraarterial or intravenous digital subtraction angiography. Two kinds of ultrasonic investigations have been defined: complete explorations when the renal artery ostium is accessible, incomplete explorations in other cases. The main difficulty preventing the exploration from being complete is obesity: all patient with an overweight of more than 20% of their theoretical weight have an incomplete exploration of at least one of their renal arteries. Furthermore, duplex sonography was not able to demonstrate polar artery in any case. When the exploration is complete, maximum systolic frequency (F max) recorded on the renal artery course, and the systolic frequency ratio of renal and aortic recordings (RAR) are two valuable criteria of significant stenosis (> 50%): mean difference between normal and stenosed arteries for these two variables is statistically significant (p < 0.01). To obtain a good specificity, pathological threshold have been fixed at F max > 3,500 Hz and RRA > 2.5. When the exploration in incomplete, ascending time (asc. T) and resistance index (RI) of doppler recording obtained in the renal hilum are two valuable criteria for severe stenosis (> 80%), or occlusion: the mean between stenosed and non stenosed arteries is statistically different (p < 0.001 and p < 0.002).(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是对肾动脉狭窄的不同超声标准进行严格验证,并展示双功超声在肾动脉狭窄筛查中的性能。67例患者接受了超声技术检查,并将双功超声的结果与动脉内或静脉数字减影血管造影的结果进行了比较。定义了两种超声检查:当肾动脉开口可及的时候进行完整检查,在其他情况下进行不完整检查。妨碍完整检查的主要困难是肥胖:所有体重超过其理论体重20%的患者,其至少一条肾动脉的检查是不完整的。此外,双功超声在任何情况下都无法显示极动脉。当检查完整时,在肾动脉走行上记录的最大收缩期频率(F max)以及肾动脉与主动脉记录的收缩期频率比(RAR)是显著狭窄(>50%)的两个有价值的标准:这两个变量在正常动脉和狭窄动脉之间的平均差异具有统计学意义(p<0.01)。为了获得良好的特异性,将病理阈值设定为F max>3500 Hz和RRA>2.5。当检查不完整时,在肾门获得的多普勒记录的上升时间(asc.T)和阻力指数(RI)是严重狭窄(>80%)或闭塞的两个有价值的标准:狭窄动脉和非狭窄动脉之间的平均值有统计学差异(p<0.001和p<0.002)。(摘要截短于250字)