Flores T, Carbajo S, Carbajo-Pérez E
Department of Pathology, Hospital Clinico of Salamanca, Spain.
Anal Cell Pathol. 1994 Jan;6(1):3-8.
The proportions of cells with a high expression of AgNORs, as directly assessed under the light microscope, and those of Ki-67-immunoreactive cells were divided into three categories (low, < 25%; intermediate, 25-50%; high, > 50%) and compared to a series of 41 human biopsy samples of lymphoid tissue. Irrespective of histological features a strong correlation was found between both variables (contingency coefficient = 0.8; P < 0.001). It is concluded that direct evaluation of cells with a high expression of AgNORs may serve as an index of proliferative activity in biopsy samples of lymphoid tissue.
在光学显微镜下直接评估的具有高表达核仁组成区嗜银蛋白（AgNORs）的细胞比例以及Ki-67免疫反应性细胞的比例被分为三类（低，<25%；中，25 - 50%；高，>50%），并与41例人类淋巴组织活检样本进行比较。无论组织学特征如何，在这两个变量之间均发现了强相关性（列联系数 = 0.8；P < 0.001）。得出的结论是，对具有高表达AgNORs的细胞进行直接评估可作为淋巴组织活检样本中增殖活性的一个指标。
