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[Transplantation of vital islands of Langerhans in diabetic animal recipients].

作者信息

Rumpf K D, Schweitzer G, Pichlmayr R, Trautschold I

出版信息

Langenbecks Arch Chir. 1975;Suppl:103-5.

PMID:813070
Abstract

Pancreatic islets of 300 g-Lewis-rats have been transplanted to 200 g streptozotocin-diabetic rats after preparation by manual-dissection method and by the Ficoll-method. The transplantation of more than 500 intact pancreatic islets into the peritoneal cavity of streptozotocin-diabetic-Lewis-rats results in a significant reduction of hyperglycemia, an increase of insulin output and a restoration of weight gain. It is suggested, that it is best to use the glucose-tolerance-test for interpretation of insulin-output and insulin-effect.

摘要

引用本文的文献

1
Transplantation of isologous islets of Langerhans in diabetic rats. Long-term immunohistochemical results.
Acta Diabetol Lat. 1977 Sep-Dec;14(5-6):199-210. doi: 10.1007/BF02580968.
2
[Methods of evaluating the function of transplanted islets of Langerhans (author's transl)].
Langenbecks Arch Chir. 1977 Apr 22;343(4):293-305. doi: 10.1007/BF01300576.

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