Birch B R, Ratan P, Morley R, Cumming J, Smart C J, Jenkins J D
Southampton University Hospitals, UK.
Br J Urol. 1994 Feb;73(2):155-9. doi: 10.1111/j.1464-410x.1994.tb07484.x.
The value of 2% lignocaine gel as a topical anaesthetic for flexible cystoscopy in men was tested in a prospective, randomized, double-blind, placebo controlled trial.
A total of 138 patients were entered into the study. Group A patients (n = 75) received 10 ml of 2% lignocaine gel intraurethrally whilst 10 ml of plain lubricating gel was instilled in the remaining 63 patients (Group B). Patient discomfort was recorded by means of a four-point descriptive pain scale (completed by both surgeon and patient) and a 100 mm non-graphic rating visual analogue scale (patient only).
The results showed no significant difference between the two treatments irrespective of the method of recording.
This study shows that 2% lignocaine gel offers no advantage over plain lubricating gel in providing analgesia for flexible cystoscopy. In this situation good lubrication may be a more important factor than topical anaesthesia.
在一项前瞻性、随机、双盲、安慰剂对照试验中，测试2%利多卡因凝胶作为男性软性膀胱镜检查局部麻醉剂的价值。
共有138例患者纳入本研究。A组患者（n = 75）经尿道接受10 ml 2%利多卡因凝胶，其余63例患者（B组）注入10 ml普通润滑凝胶。通过四点描述性疼痛量表（由外科医生和患者共同完成）和100 mm非图形评分视觉模拟量表（仅由患者完成）记录患者不适情况。
无论采用何种记录方法，两种治疗方法之间均无显著差异。
本研究表明，在为软性膀胱镜检查提供镇痛方面，2%利多卡因凝胶并不比普通润滑凝胶更具优势。在这种情况下，良好的润滑可能比局部麻醉更为重要。
