Olatunji P O, Falusi A G, Shokunbi W A, Essien E M
Department of Haematology, Faculty of Health Sciences, University of Ilorin, Nigeria.
Cent Afr J Med. 1993 May;39(5):102-4.
The Packed Cell Volume (PCV), reticulocyte count and Hb A2 were determined in 28 patients during the period of malaria parasitaemia and 14 days after effective treatment. The Hb A2 was determined by cellulose acetate haemoglobin electrophoresis in alkaline medium followed by elution in water. There was no statistically significant difference between the PCV during the period of parasitaemia and that after treatment (p > 0.05). The Hb A2 level did not show any significant difference during and after treatment of malaria (p = 0.05). The correlation coefficient between absolute parasite count and Hb A2 level was -0.22 (p = 0.251). It is concluded that malaria parasitaemia does not induce a significant change in the level of Hb A2.
在28例疟疾寄生虫血症患者以及有效治疗后14天内，测定了血细胞比容（PCV）、网织红细胞计数和Hb A2。Hb A2通过在碱性介质中进行醋酸纤维素血红蛋白电泳，然后用水洗脱来测定。寄生虫血症期间的PCV与治疗后的PCV之间无统计学显著差异（p>0.05）。疟疾治疗期间和治疗后的Hb A2水平无显著差异（p = 0.05）。绝对寄生虫计数与Hb A2水平之间的相关系数为-0.22（p = 0.251）。得出的结论是，疟疾寄生虫血症不会导致Hb A2水平发生显著变化。
