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与健康受试者相比,痉挛性脊髓损伤患者在肌肉拉伸后H反射的抑制作用较小。

H-reflexes are less depressed following muscle stretch in spastic spinal cord injured patients than in healthy subjects.

作者信息

Nielsen J, Petersen N, Ballegaard M, Biering-Sørensen F, Kiehn O

机构信息

Department of Medical Physiology, Panum Institute, University of Copenhagen, Denmark.

出版信息

Exp Brain Res. 1993;97(1):173-6. doi: 10.1007/BF00228827.

DOI:10.1007/BF00228827
PMID:8131827
Abstract

The size of the soleus H-reflex was measured after a slow (17 deg/s) passive stretch of ankle plantarflexors and compared to its control size without muscle stretch in ten neurologically healthy subjects and in six spastic spinal-cord-injured patients. Two seconds after the end of the stretch, the size of the H-reflex was reduced to about 30% of its pre-stretch size in the healthy subjects. The depression remained for 10-15 s. In the spastic, spinal-cord-injured patients, stretch caused significantly less reduction in the size of the H-reflex. The H-reflex also regained its pre-stretch size much faster than in healthy subjects. We suggest that the smaller depression of the H-reflex observed in spastic patients may be involved in the pathophysiology of spasticity.

摘要

在十名神经功能正常的受试者和六名痉挛性脊髓损伤患者中,对踝跖屈肌进行缓慢(17度/秒)被动拉伸后,测量比目鱼肌H反射的大小,并将其与未进行肌肉拉伸时的对照大小进行比较。拉伸结束两秒后,健康受试者的H反射大小降至拉伸前大小的约30%。这种抑制持续10 - 15秒。在痉挛性脊髓损伤患者中,拉伸导致H反射大小的减小明显较少。H反射恢复到拉伸前大小的速度也比健康受试者快得多。我们认为,在痉挛患者中观察到的H反射较小程度的抑制可能与痉挛的病理生理学有关。

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