Ize Lamache L, Carrasco A, Ordóñez A, López Martínez R
Prensa Med Mex. 1975 Sep-Oct;40(9-10):285-90.
Parenteral nutrition has completely modified the prognosis in a variety of illnesses of digestive tract. The method is not devoid of complications, and septicemias, particularly those originated by fungii of the Candida species, have been informed to occur with an alarming frequency of up to 23%. The patient on parenteral nutrition is an ideal prey for this kind of infection, but if the technic and the metabolic control are brought down considerably. In 30 patients of the Department of Gastroenterology at the Hospital General, Centro Médico Nacional, Instituto Mexicano del Seguro Social, we have studied the frequency and evolution of Candida infections, detected before or during the treatment with parenteral nutrition to know the influence of the method on this type of host-parasite relationship. In the initial cultures 60% of the patients develop Candida in one or several regions; percentage increased to 63.3% at the end of 15 days and decreased spontaneously to 33% at the end of the treatment on the 30 patients we did not observe a septicemia due to Candida. We conclude that parenteral nutrition, while correcting the nutritional state of the patient, with a good technic, favors the spontaneous withdrawal of the fungii, without the necessary specific treatment.
胃肠外营养已彻底改变了多种消化道疾病的预后。该方法并非没有并发症，败血症，尤其是由念珠菌属真菌引起的败血症，据报道其发生率高达23%，令人担忧。接受胃肠外营养的患者是这类感染的理想目标，但前提是技术操作和代谢控制大幅下降。在墨西哥社会保障局国家医学中心总医院胃肠病科的30例患者中，我们研究了念珠菌感染的频率和演变情况，这些感染在胃肠外营养治疗前或治疗期间被检测到，以了解该方法对这种宿主-寄生虫关系的影响。在初始培养中，60%的患者在一个或几个部位出现念珠菌；15天后这一比例增至63.3%，在治疗结束时自发降至33%。在我们研究的30例患者中，未观察到由念珠菌引起的败血症。我们得出结论，胃肠外营养在通过良好的技术纠正患者营养状况的同时，有利于真菌的自然清除，无需进行必要的特异性治疗。
