Ray D, Saha K, Jairaj P S, Kanagasabhapathy A S
Department of Chest Diseases, Christian Medical College Vellore.
Indian J Med Res. 1993 Dec;98:278-82.
Serum IgE levels were measured by the radioimmunoassay technique in the sera of 53 patients with neoplastic chest diseases. Forty seven patients had malignant chest tumours and another 6 had benign tumours or mediastinal cysts. They included 33 smokers and 20 non-smokers. For comparison, 30 normal non-smoking controls matched for age and sex were included. The serum IgE levels in patients with chest malignancies showed an increase as compared to controls. The IgE levels increased significantly in adenocarcinoma (P < 0.01) and squamous cell carcinoma (P < 0.001), while they were not raised in poorly differentiated carcinoma. There was no significant difference between the serum IgE levels of 32 smokers and 15 non-smokers with malignant chest tumours.
采用放射免疫分析技术测定了53例胸部肿瘤患者血清中的IgE水平。其中47例患有恶性胸部肿瘤，另外6例患有良性肿瘤或纵隔囊肿。患者中有33名吸烟者和20名非吸烟者。为作比较，纳入了30名年龄和性别匹配的正常非吸烟对照者。与对照组相比，胸部恶性肿瘤患者的血清IgE水平有所升高。腺癌患者的IgE水平显著升高（P < 0.01），鳞状细胞癌患者的IgE水平显著升高（P < 0.001），而低分化癌患者的IgE水平未升高。32名吸烟的胸部恶性肿瘤患者与15名不吸烟的胸部恶性肿瘤患者的血清IgE水平之间无显著差异。
