Investigations on some coagulability tests in atherosclerosis.

Coagulation and fibrinolysis were investigated in a group of atherosclerosis patients, a group of neonates and a control group, determining the clot retraction time, the amount and quality of the blood platelets, and euglobulin lysis time. The results showed that fibrinolytic activity values are about equal in the two experimental groups, whereas clot retraction time, number of thrombocytes, thrombocyte adhesiveness, and agglutination sharply differed. Hyperadhesiveness and hyperagglutination were found in 75% of the atherosclerosis patients, with a clot retraction time of 79% and 290,000 thrombocytes/mm3 as compared to the hypoadhesiveness and hypoagglutination found in all the neonates, in which clot retraction was 43% and the number of thrombocytes 115,000. All values differed from those of the control lot.