Rondier J, Cayla J, Debièvre J, Moutounet J, Chevrot A, Delbarre F
Rev Rhum Mal Osteoartic. 1975 Oct;42(10):601-12.
The authors observed 10 blocks of from 2 to 8 vertebrae in 7 patients whose spines were affected by Paget's disease. The morphological characteristics of these blockages were for the most part similar to those of acquired synostoses, the corresponding articular apophyses appearing to be fused in the majority of cases. Even without a radiograph taken before the formation of the blocks, the fact that there had been progression of the synostosis between certain vertebrae indicates the probability of an acquired origin. The prevalence of these vertebral blocks in a group of 76 patients suffering from Paget's disease of the spine (12 percent, or 9 patients with 13 blocks) was significantly higher than that found in a population of 200 persons not suffering from Paget's disease, (3 percent, or 6 patients with 6 blocks) and among the 13 blocks discovered in the patients with Paget's disease only 3 were formed of vertebrae unaffected by deforming osteitis. These facts suggest that the formation of a vertebral block may be favoured by Paget's disease localized in the vertebral column. This is a little recognized idea even though it was formulated in Schmorl's work at the beginning of this century.
作者观察了7例患有佩吉特病的患者的脊柱，这些患者有10个包含2至8个椎骨的椎骨块。这些椎骨块的形态特征在很大程度上与后天性融合相似，在大多数情况下，相应的关节突似乎融合在一起。即使在椎骨块形成之前没有拍摄X光片，某些椎骨之间融合进展的事实也表明其起源可能是后天性的。在一组76例患有脊柱佩吉特病的患者中，这些椎骨块的发生率（12%，即9例患者有13个椎骨块）明显高于200名未患佩吉特病的人群（3%，即6例患者有6个椎骨块），在患有佩吉特病的患者中发现的13个椎骨块中，只有3个是由未受变形性骨炎影响的椎骨形成的。这些事实表明，局限于脊柱的佩吉特病可能有利于椎骨块的形成。尽管这个观点在本世纪初施莫尔的著作中就已提出，但仍鲜为人知。
