Yamamura A, Takamura Y, Yamaki T, Nakagawa T, Hashi K
Shinsapporo Neurosurgical Hospital.
No Shinkei Geka. 1994 Mar;22(3):265-8.
We encountered one case of progressing stroke caused by severe basilar artery stenosis. The patient was treated with emergent percutaneous transluminal angioplasty (PTA) with satisfactory results. A 54 year-old woman was admitted 15 minutes after the sudden onset of rt. hemiparesis, rt. hemidysesthesia, dysarthria and consciousness disturbance. CT scan on admission showed no abnormal findings. The consciousness level of the patient deteriorated rapidly from JCS 1 to JCS 20 within 30 minutes from the ictus. An emergent angiogram revealed severe basilar artery stenosis at its middle portion and poorly developed collateral circulation. One hour after the stroke occurred, PTA was performed. Using a 3mm diameter balloon catheter, we introduced the balloon into the stenotic lesion and inflated it 6 times from 4 atm to 8 atm pressure. The patient recovered immediately on the operating table improving from JCS 20 to JCS 1. Rt. hemiparesis also improved. Follow-up MRI showed a small area of ischemic change in the brain stem, but no large infarction appeared. The patient was discharged with no neurosurgical deficits after 30 days of PTA. PTA for basilar artery stenosis is still a controversial subject. One reason is the risk of basilar artery perforating branches occlusion by balloon catheter and the other is the difficulty of introducing a flexible balloon catheter into the basilar artery beyond the acute angulation of the vertebral artery. If those two problems were solved, PTA would be the first-choice therapy for basilar artery stenosis in both acute and chronic stages.
我们遇到一例由严重基底动脉狭窄导致的进展性卒中病例。该患者接受了急诊经皮腔内血管成形术(PTA),效果满意。一名54岁女性在突发右侧偏瘫、右侧半身感觉障碍、构音障碍和意识障碍15分钟后入院。入院时CT扫描未见异常。患者的意识水平在发病后30分钟内从日本昏迷评分(JCS)1迅速恶化为JCS 20。急诊血管造影显示基底动脉中部严重狭窄,侧支循环发育不良。卒中发生1小时后进行了PTA。我们使用直径3mm的球囊导管,将球囊置入狭窄病变处,并在4个大气压至8个大气压的压力下充气6次。患者在手术台上立即恢复,从JCS 20改善为JCS 1。右侧偏瘫也有所改善。随访MRI显示脑干有小面积缺血改变,但未出现大面积梗死。PTA术后30天,患者出院,无神经外科后遗症。基底动脉狭窄的PTA仍然是一个有争议的话题。一个原因是球囊导管有导致基底动脉穿支闭塞的风险,另一个原因是将可弯曲的球囊导管引入超过椎动脉急性成角处的基底动脉存在困难。如果这两个问题得到解决,PTA将成为急性和慢性基底动脉狭窄的首选治疗方法。