Diaz M, Bockisch A, Hahn K, Walgenbach S
Klinik und Poliklinik, Johannes Gutenberg-Universität Mainz, FRG.
Nuklearmedizin. 1994 Feb;33(1):42-5.
Radionuclide imaging of the parathyroid gland is used in the preoperative localization of parathyroid adenoma. Until recently radionuclide imaging of parathyroid tumors was performed using a dual-tracer subtraction technique with 201TI and 99mTcO4-. As an alternative radionuclide imaging with 99mTc-sestamibi (MIBI) has been introduced some years ago. The utility of preoperative parathyroid localization lies in its ability to direct surgical exploration, particularly of ectopic localizations. We present two cases of parathyroid adenoma in which radionuclide imaging with 99mTc-MIBI was successful in detecting atypical locations. In the first case remaining primary hyperparathyroidism was caused by a mediastinal gland. The second case suffered from a recurrence of secondary hyperparathyroidism caused by hyperplasia of the autotransplanted gland after removal of all four parathyroid glands.
甲状旁腺的放射性核素成像用于甲状旁腺腺瘤的术前定位。直到最近，甲状旁腺肿瘤的放射性核素成像还是使用201铊和99m锝高锝酸盐的双示踪剂减影技术来进行。作为一种替代方法，几年前已引入了用99m锝-甲氧基异丁基异腈（MIBI）进行放射性核素成像。术前甲状旁腺定位的作用在于其能够指导手术探查，尤其是对异位定位的探查。我们报告两例甲状旁腺腺瘤病例，其中用99m锝-MIBI进行放射性核素成像成功检测到了非典型位置。第一例中，残留的原发性甲状旁腺功能亢进是由纵隔腺体引起的。第二例患者在切除所有四个甲状旁腺后，因自体移植腺体增生导致继发性甲状旁腺功能亢进复发。
