Lahoti C, Schinella R, Rangwala A F, Lee M, Mizrachi H
Department of Pathology, Monmouth Medical Center, Long Branch, New Jersey.
Urology. 1994 Mar;43(3):389-93. doi: 10.1016/0090-4295(94)90087-6.
We studied 5 cases of carcinosarcoma of the urinary bladder. Immunoperoxidase studies were performed to identify the nature of the tumor and to establish the diagnosis. We suggest that these tumors represent a transition of epithelial to mesenchymal malignancy. Three of our patients had a history of radiation therapy prior to development of carcinosarcoma; of which 2 had a long interval between exposure to radiation and tumor development. Radiation is a risk factor for endometrial carcinosarcoma, and in this report we strongly suggest such an association for the urinary bladder.
我们研究了5例膀胱癌肉瘤。进行免疫过氧化物酶研究以确定肿瘤的性质并确立诊断。我们认为这些肿瘤代表了从上皮性恶性肿瘤向间叶性恶性肿瘤的转变。我们的3例患者在癌肉瘤发生之前有放射治疗史；其中2例在接受放射治疗与肿瘤发生之间间隔时间较长。放射是子宫内膜癌肉瘤的一个危险因素，在本报告中我们强烈提示膀胱癌肉瘤也存在这种关联。
