Graber H U, Martig J
Klinik für Nutztiere und Pferde, Universität Bern.
Zentralbl Veterinarmed A. 1993 Nov-Dec;40(9-10):690-6. doi: 10.1111/j.1439-0442.1993.tb00685.x.
The intention of this paper was to describe a reliable method for the diagnosis of cardiomyopathy (CMP) in adult cattle and, in particular, a clear distinction between CMP and inflammatory heart disease (IHD). In a first study we performed a linear discriminant analysis using serum and urine electrolyte concentrations (sodium, potassium, calcium, magnesium, chloride, phosphate, iron, creatinine) of 33 CMP-affected and 35 healthy cattle. This analysis allowed to classify all the animals of both animal groups correctly. In a second study, we examined the clotting reaction of the glutaraldehyde coagulation test (GCT) in cardiomyopathy (n = 49), inflammatory heart diseases (n = 9) and in healthy cows (n = 35). 96% of the CMP-sick and all the control animals showed a clotting time above 10 minutes. In the IHD group, the clotting time was always below 10 minutes. In a third study, we applied the combination of discriminant analysis and GCT to a new set of CMP- (n = 14) and IHD-affected (n = 9) as well as to healthy cattle (n = 15). The classification was correct in 93% of the CMP-sick and in all the IHD-affected and the control animals. The results are discussed.
本文旨在描述一种诊断成年牛心肌病（CMP）的可靠方法，尤其是明确区分CMP与炎症性心脏病（IHD）。在第一项研究中，我们对33头患有CMP的牛和35头健康牛的血清和尿液电解质浓度（钠、钾、钙、镁、氯、磷酸盐、铁、肌酐）进行了线性判别分析。该分析能够正确地对两组动物进行分类。在第二项研究中，我们检测了戊二醛凝固试验（GCT）在心肌病（n = 49）、炎症性心脏病（n = 9）以及健康奶牛（n = 35）中的凝血反应。96%的患CMP病牛和所有对照动物的凝血时间超过10分钟。在IHD组中，凝血时间始终低于10分钟。在第三项研究中，我们将判别分析和GCT的组合应用于一组新的患CMP的牛（n = 14）、患IHD的牛（n = 9）以及健康牛（n = 15）。93%的患CMP病牛以及所有患IHD的牛和对照动物的分类是正确的。对结果进行了讨论。
