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低剂量白细胞介素-2可治愈大型牛眼鳞状细胞癌。

Low doses of interleukin-2 can cure large bovine ocular squamous cell carcinoma.

作者信息

Den Otter W, Hill F W, Klein W R, Koten J W, Steerenberg P A, De Mulder P H, Rutten V P, Ruitenberg E J

机构信息

Department of Pathology, Academical Hospital Utrecht, The Netherlands.

出版信息

Anticancer Res. 1993 Nov-Dec;13(6B):2453-5.

PMID:8135482
Abstract

Four cows bearing large Ocular Squamous Cell Carcinomas (BOSCC) were treated by 10 intratumoral injections (Monday-Friday for 2 consecutive weeks) of 200,000 U Interleukin-2 (Cetus). Tumors regressed in 2 out of 4 cases. This result shows that even large tumors may regress after local IL-2 treatment.

摘要

对四头患有大的眼鳞状细胞癌(BOSCC)的奶牛,连续两周(周一至周五)每周进行10次瘤内注射200,000单位白细胞介素-2(Cetus公司生产)。4例中有2例肿瘤消退。这一结果表明,即使是大的肿瘤在局部注射白细胞介素-2治疗后也可能消退。

相似文献

1
Low doses of interleukin-2 can cure large bovine ocular squamous cell carcinoma.低剂量白细胞介素-2可治愈大型牛眼鳞状细胞癌。
Anticancer Res. 1993 Nov-Dec;13(6B):2453-5.
2
Local interleukin-2 and interleukin-12 therapy of bovine ocular squamous cell carcinomas.牛眼鳞状细胞癌的局部白细胞介素-2和白细胞介素-12治疗
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Hyperthermia for treatment of ocular squamous cell tumors in cattle.
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Clinico-pathological aspects of immunotherapy by intralesional injection of BCG cell walls or live BCG in bovine ocular squamous cell carcinoma.通过病灶内注射卡介苗细胞壁或活卡介苗对牛眼鳞状细胞癌进行免疫治疗的临床病理学方面
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Radioactive gold in the treatment of ocular squamous cell carcinoma of cattle.放射性金在牛眼鳞状细胞癌治疗中的应用
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Therapy of bovine ocular squamous-cell carcinoma with local doses of interleukin-2: 67% complete regressions after 20 months of follow-up.局部注射白细胞介素-2治疗牛眼鳞状细胞癌:随访20个月后完全缓解率达67%。
Cancer Immunol Immunother. 1995 Jul;41(1):10-4. doi: 10.1007/BF01788954.
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Local interleukin-2 therapy in bovine ocular squamous cell carcinoma. A pilot study.牛眼鳞状细胞癌的局部白细胞介素-2治疗。一项试点研究。
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引用本文的文献

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Local therapy of cancer with free IL-2.使用游离白细胞介素-2对癌症进行局部治疗。
Cancer Immunol Immunother. 2008 Jul;57(7):931-50. doi: 10.1007/s00262-008-0455-z.
2
Locoregional IL-2 low dose applications for gastrointestinal tumors.局部区域低剂量白细胞介素-2用于胃肠道肿瘤的治疗
World J Gastroenterol. 2005 Sep 21;11(35):5525-9. doi: 10.3748/wjg.v11.i35.5525.
3
Local interleukin 2 therapy is most effective against cancer when injected intratumourally.局部白细胞介素2疗法在瘤内注射时对癌症最有效。
Cancer Immunol Immunother. 2005 Jul;54(7):647-54. doi: 10.1007/s00262-004-0627-4. Epub 2005 Feb 1.
4
Comparison of the efficacy of local treatment of equine sarcoids with IL-2 or cisplatin/IL-2.白细胞介素-2或顺铂/白细胞介素-2对马肉瘤进行局部治疗的疗效比较。
Cancer Immunol Immunother. 2003 Mar;52(3):179-84. doi: 10.1007/s00262-002-0369-0. Epub 2003 Feb 4.
5
Therapy of bovine ocular squamous-cell carcinoma with local doses of interleukin-2: 67% complete regressions after 20 months of follow-up.局部注射白细胞介素-2治疗牛眼鳞状细胞癌:随访20个月后完全缓解率达67%。
Cancer Immunol Immunother. 1995 Jul;41(1):10-4. doi: 10.1007/BF01788954.