Kniemeyer H W, Sandmann W, Schwindt C, Grabitz K, Torsello G, Stühmeier K
Abteilung für Gefässchirurgie und Nierentransplantation, Heinrich-Heine-Universität Düsseldorf.
Clin Investig. 1993 Dec;72(1):40-5. doi: 10.1007/BF00231115.
Thrombectomy with arteriovenous fistula was performed between 1977 and 1988 in 103 patients (41 females, 62 males, mean age 46.7 years, 114 involved extremities) with embolizing deep-vein thrombosis (DVT). The sole aim of the surgical procedure was prevention of recurrent embolization. On the basis of the proximal extent of the thrombosis the source of embolization was identified as the iliac veins or inferior vena cava in 63% of the patients; 48% presented with a post-phlebitic vein and/or an older thrombosis, and 46% had already had recurrent pulmonary emboli. Unsuccessful aggressive procedures had been carried out previously in 11%. The rate of intraoperative pulmonary embolism (PE) was 3% (one fatal case). The perioperative mortality was 6.8%, but only one death was related to the surgical treatment itself. During follow-up (8-140 months postoperatively, mean 55 +/- 34 months) late recurrent PE was confirmed in two patients (antithrombin III deficiency, contralateral DVT) and was reported as the suspected cause of death in a third (3.6%). Venous thrombectomy with arteriovenous fistula is a reliable and effective procedure for management of embolizing DVT and is indicated especially in young patients. The rates of early- and late-recurrent PE are low, introduction of artificial material into the vein can be avoided, and long-term preservation of valve function is occasionally possible.
1977年至1988年间,对103例(41例女性,62例男性,平均年龄46.7岁,累及114个肢体)发生栓塞性深静脉血栓形成(DVT)的患者进行了动静脉瘘血栓切除术。手术的唯一目的是预防复发性栓塞。根据血栓形成的近端范围,63%的患者栓塞源被确定为髂静脉或下腔静脉;48%的患者出现静脉炎后静脉和/或陈旧性血栓形成,46%的患者已经发生复发性肺栓塞。11%的患者此前曾进行过无效的积极治疗。术中肺栓塞(PE)发生率为3%(1例致命病例)。围手术期死亡率为6.8%,但只有1例死亡与手术治疗本身有关。在随访期间(术后8 - 140个月,平均55±34个月),2例患者(抗凝血酶III缺乏,对侧DVT)确诊为晚期复发性PE,第3例患者疑似死于复发性PE(3.6%)。动静脉瘘静脉血栓切除术是治疗栓塞性DVT的一种可靠且有效的方法,尤其适用于年轻患者。早期和晚期复发性PE的发生率较低,可以避免将人工材料引入静脉,偶尔还可能长期保留瓣膜功能。