乙型肝炎病毒复制
Hepatitis B virus replication.
作者信息
Nassal M, Schaller H
机构信息
Zentrum für Molekulare Biologie, Universität Heidelberg, Germany.
出版信息
Trends Microbiol. 1993 Sep;1(6):221-8. doi: 10.1016/0966-842x(93)90136-f.
PMID:8137119
Abstract
Hepatitis B virus (HBV) is the causative agent of B-type hepatitis in humans and the prototypic member of the hepadnaviruses. It is a small enveloped DNA virus that replicates via reverse transcription. Although hepadnaviruses are similar to retroviruses in basic life cycle and genome organization, recent studies have revealed several unique hepadnaviral strategies that optimize exploitation of their extremely small circular DNA genomes.
摘要
乙型肝炎病毒（HBV）是人类B型肝炎的病原体，也是嗜肝DNA病毒科的原型成员。它是一种通过逆转录进行复制的小型包膜DNA病毒。尽管嗜肝DNA病毒在基本生命周期和基因组组织方面与逆转录病毒相似，但最近的研究揭示了几种独特的嗜肝DNA病毒策略，这些策略优化了对其极小环状DNA基因组的利用。
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