Wang L Y
PLA General Hospital, Beijing.
Zhonghua Fu Chan Ke Za Zhi. 1993 Dec;28(12):711-3, 758.
The study was designed on blood visco-elasticity of normal pregnant and pregnancy induced hypertension (PIH) women. Visco-component (eta'), elastic-component (eta") and storage modulus (G') decreased significantly during the 1st trimester of pregnancy, but rose slowly in the 3rd trimester. eta' was the most significant and it revealed an inverse correlation with neonate birth weight. There were no changes of eta', eta" and G' in women with mild PIH, but they rose markedly in groups with moderate and severe PIH. In conclusion, abnormal blood viscosity and elasticity, i.e. an increase of RBC aggregation and/or a decrease of RBC deformability, may be an important abnormal hemorheological changes in PIH.
该研究针对正常孕妇和妊娠高血压综合征(PIH)妇女的血液粘弹性展开。粘性成分(η')、弹性成分(η")和储能模量(G')在妊娠早期显著下降,但在妊娠晚期缓慢上升。η'变化最为显著,且与新生儿出生体重呈负相关。轻度PIH妇女的η'、η"和G'无变化,但中度和重度PIH组中这些指标显著上升。总之,血液粘度和弹性异常,即红细胞聚集增加和/或红细胞变形性降低,可能是PIH重要的血液流变学异常变化。