稳定型心绞痛患者硝苯地平突然停药后的撤药现象。
Withdrawal phenomenon after abrupt cessation of nifedipine in stable angina pectoris.
作者信息
Martsevich S Y, Koutishenko N, Metelitsa V I
机构信息
Department of Preventive Pharmacology, Research Centre for Preventive Medicine of Russia, Moscow.
出版信息
Int J Cardiol. 1993 Dec 31;42(3):298-301. doi: 10.1016/0167-5273(93)90065-o.
PMID:8138342
Abstract
We investigated the effect of abrupt cessation of nifedipine after regular administration (20 mg, four times daily) for 5 weeks in seven patients with stable angina pectoris. A rebound decrease in exercise tolerance and increase of exercise-induced myocardial ischaemia were registered on the first day of nifedipine withdrawal.
摘要
我们研究了7例稳定型心绞痛患者在规律服用硝苯地平（20毫克，每日4次）5周后突然停药的影响。在硝苯地平停药的第一天，记录到运动耐量出现反弹性下降以及运动诱发的心肌缺血增加。
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