Kamei-Hayashi K, Oshino R, Hara S
Laboratory of Biochemistry, Kobe Yamate Women's College, Kobe.
J Biochem. 1993 Dec;114(6):835-41. doi: 10.1093/oxfordjournals.jbchem.a124265.
The amino acid sequence of glutathione S-transferase a from guinea pig liver was determined. Glutathione S-transferase a was composed of two identical subunits, each comprising 218 amino acid residues. The amino acid sequence of glutathione S-transferase a exhibited 73% homology with that of human glutathione S-transferase Ha, 69% with that of rat glutathione S-transferase Ya, and 68% with that of rat glutathione S-transferase Yc, which are known to belong to class Alpha. From the above result, together with previous observations on its substrate specificity, it was concluded that glutathione S-transferase a belonged to class Alpha.
