Cleveland D B, Chen S Y, Allen C M, Ahing S I, Svirsky J A
Temple University School of Medicine, Department of Pathology, Philadelphia, PA 19140.
Oral Surg Oral Med Oral Pathol. 1994 Feb;77(2):147-53. doi: 10.1016/0030-4220(94)90277-1.
Adult rhabdomyoma is a rare benign tumor of skeletal muscle origin that frequently arises from musculature of the head and neck region. In this study we report five cases of adult rhabdomyoma. Light and electron microscopic examination revealed the typical cellular features as described by others. The results of immunophenotyping and quantitation of nucleolar organizer regions were consistent for a benign skeletal muscle tumor. Epstein-Barr virus and human papillomavirus genomic DNA could not be detected by in situ hybridization.
成人横纹肌瘤是一种罕见的起源于骨骼肌的良性肿瘤,常发生于头颈部肌肉组织。在本研究中,我们报告了5例成人横纹肌瘤病例。光镜和电镜检查显示出与其他文献所描述的典型细胞特征。免疫表型分析和核仁组织区定量结果均符合良性骨骼肌肿瘤的表现。原位杂交未检测到爱泼斯坦-巴尔病毒和人乳头瘤病毒基因组DNA。