Teutsch H F
Histochemistry. 1975 Dec 8;45(3):227-35. doi: 10.1007/BF00507697.
Adult ureter epithelium of the golden hamster is found to be multilayered but not stratified. All epithelial cells are in contact with the basement membrane and thereby get into close vicinity to the underlying dense capillary network of the lamina propria. By this diffusion distances for nutritial fluids are kept very short. As can be seen from high glycoproteid and glycolipid content as well as high SDH, G6PDH and LDH activities, superficial cells are higher differentiated than intermediate and basal cells where enzyme activities and concentrations of glycoproteids and glycolipids are always found to be lower. From low RNA-concentrations in all layers of ureter epithelium, high G6PDH activity and glycolipid content, it is concluded that pentose-phosphate cycle primarily functions as donator of reduced NADP for lipid synthesis. Dual presence of SDH and LDH activities in ureter epithelium is seen in hypothetical connection with periods of changing oxygen supply caused by ureter peristalsis. Small amounts of glycogen are metabolically rather inactive as revealed by low or absent phosphorylase and UDPGGT activities.
金黄仓鼠的成年输尿管上皮为多层，但并非复层。所有上皮细胞均与基底膜接触，从而与固有层下方致密的毛细血管网紧密相邻。通过这种方式，营养液体的扩散距离得以保持很短。从高糖蛋白和糖脂含量以及高SDH、G6PDH和LDH活性可以看出，表层细胞比中间层和基底细胞分化程度更高，中间层和基底细胞的酶活性以及糖蛋白和糖脂的浓度总是较低。从输尿管上皮各层的低RNA浓度、高G6PDH活性和糖脂含量可以得出结论，磷酸戊糖循环主要作为还原型NADP的供体用于脂质合成。输尿管上皮中SDH和LDH活性的双重存在被认为与输尿管蠕动引起的氧气供应变化时期存在假设联系。少量糖原在代谢上相当不活跃，这通过低或缺乏磷酸化酶和UDPGGT活性得以揭示。
