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癫痫持续状态的现代概念。

Modern concepts of status epilepticus.

作者信息

Celesia G G

出版信息

JAMA. 1976 Apr 12;235(15):1571-4.

PMID:814259
Abstract

Among 60 cases of status epilepticus, there were 45 cases of convulsive status and 15 cases of nonconvulsive or confusional status. In 37 cases, status was due to an identifiable cause. The most frequent etiologic factors were vascular (nine cases), traumatic (seven cases), and metabolic (five cases). Four patients with metabolic encephalopathy had focal status. While the possibility of expanding lesions should be investigated in every case of convulsive status, a complete metabolic screening is also necessary. Non-convulsive status was represented by two cases of psychomotor status and 13 cases of absence status. Clinically, these cases were characterized by various impairments of intellectual functioning and confusion. Diagnosis was determined by characteristic changes in the electroencephalogram. Aggressive treatment is indicated by one or more of the major anticonvulsants, supplemented by adequate oxygenation and maintenance of biochemical homeostasis.

摘要

在60例癫痫持续状态患者中,惊厥性癫痫持续状态45例,非惊厥性或精神错乱性癫痫持续状态15例。37例患者的癫痫持续状态有明确病因。最常见的病因是血管性(9例)、创伤性(7例)和代谢性(5例)。4例代谢性脑病患者出现局灶性癫痫持续状态。虽然对于每例惊厥性癫痫持续状态患者都应调查是否存在占位性病变,但全面的代谢筛查也是必要的。非惊厥性癫痫持续状态包括2例精神运动性癫痫持续状态和13例失神性癫痫持续状态。临床上,这些病例的特点是存在各种智力功能障碍和意识模糊。诊断通过脑电图的特征性变化来确定。主要抗惊厥药物中的一种或多种进行积极治疗,并辅以充分的氧疗和维持生化稳态。

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