Van Gijsegem F, Genin S, Boucher C
Laboratoire de Biologie Moléculaire des Relations Plantes-Microorganismes, INRA-CNRS, F-31326, Castanet Tolosan, France.
Trends Microbiol. 1993 Aug;1(5):175-80. doi: 10.1016/0966-842x(93)90087-8.
Extracellular proteins of plant and animal bacteria are important in virulence. Many of these are secreted through the type I sec-independent and the type II sec-dependent pathways. Recently, a third distinct pathway, involved in secretion of Yops, has been discovered in Yersinia. This pathway has homology with pathways in plant pathogenic bacteria that are putatively involved in the secretion of proteins active on plant cells, such as harpin and possibly some avr gene products
植物、动物和细菌的细胞外蛋白在毒力方面很重要。其中许多蛋白是通过I型不依赖Sec途径和II型依赖Sec途径分泌的。最近,在耶尔森氏菌中发现了第三条不同的途径,该途径参与Yop蛋白的分泌。此途径与植物致病细菌中的途径具有同源性,这些植物致病细菌中的途径据推测参与对植物细胞有活性的蛋白(如harpin以及可能的一些avr基因产物)的分泌。