来适可（法莫替丁）治疗消化性溃疡患者的疗效
[Effectiveness of lecedil (famotidine) in the therapy of patients with peptic ulcer].
作者信息
Grebenev A L, Sheptulin A A, Smakov G M, Kornienko A A, Trukhmanov A S
出版信息
Klin Med (Mosk). 1993;71(6):30-2.
A total of 30 patients (29 with peptic ulcer and 2 with erosive gastroduodenitis) received lecedil, a new famotidine blocker of histamine H2-receptors. The effect of the drug was not related to the dose regimen (20 mg twice or 40 once a day). In good tolerance side effects were not reported. Healing of duodenal ulcer occurred within 4 and 5 treatment weeks in 17 (85.0%) and 19 (95.0%) out of 20 patients, respectively, within 6 and 8 treatment weeks ulcer healed in 5 and 6 out of 8 gastric ulcer patients, respectively.
共有30名患者（29名患有消化性溃疡，2名患有糜烂性胃十二指肠炎症）接受了新型组胺H2受体阻滞剂雷西替丁治疗。药物疗效与给药方案（每日两次20毫克或每日一次40毫克）无关。耐受性良好，未报告有副作用。20名十二指肠溃疡患者中，分别在治疗4周和5周时，有17名（85.0%）和19名（95.0%）溃疡愈合；8名胃溃疡患者中，分别在治疗6周和8周时，有5名和6名溃疡愈合。
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