钙和β-肾上腺素能系统在甲状旁腺激素分泌调控中的作用。
Role of calcium and beta-adrenergic system in control of parathyroid hormone secretion.
作者信息
Kukreja S C, Johnson P A, Ayala G, Banerjee P, Bowser E N, Hargis G K, Williams G A
出版信息
Proc Soc Exp Biol Med. 1976 Feb;151(2):326-8. doi: 10.3181/00379727-151-39202.
In the rat, EDTA and isoproterenol stimulated PTH secretion, whereas high calcium and propranolol inhibited it. The stimulatory effects of EDTA and isoproterenol were still evident and unaltered in the presence of blocks induced by propranolol and high calcium, respectively. The findings suggest that: (i) both calcium and beta-adrenergic stimuli affect PTH secretion; and (ii) the two influences affect the PTH secretion by separate initial pathways.
在大鼠中，乙二胺四乙酸（EDTA）和异丙肾上腺素刺激甲状旁腺激素（PTH）分泌，而高钙和普萘洛尔则抑制其分泌。在分别由普萘洛尔和高钙诱导的阻断存在的情况下，EDTA和异丙肾上腺素的刺激作用仍然明显且未改变。这些发现表明：（i）钙和β-肾上腺素能刺激均影响PTH分泌；（ii）这两种影响通过不同的初始途径影响PTH分泌。
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