Scott T R, Dunnington E A, Siegel P B
Department of Poultry Science, Clemson University, South Carolina 29634-0379.
Poult Sci. 1994 Feb;73(2):346-9. doi: 10.3382/ps.0730346.
Three experiments were conducted with lines of chickens selected for high (HA) and low (LA) antibody response to sheep erythrocytes to determine their antibody responses following primary immunization with Brucella abortus. In Experiment 1, HA chicks responded to immunization with a higher total titer than LA chicks at 7 d postimmunization. At both 5 and 7 d following immunization 2-mercaptoethanol-resistant (IgG) titers were higher in HA than LA chicks. There also was a significant sex effect at 7 d in the first experiment, with males having higher total titers than females. In the second experiment, HA chicks had higher total titers at 5 d postimmunization than LA chicks, but IgG titers were similar for both lines. Total and IgG titers of HA chicks used in Experiment 3 were significantly higher than those of LA chicks at 5 and 7 d postimmunization. Both HA and LA chicks exhibited divergent antibody responses to B. abortus although they had originally been selected for antibody responsiveness to sheep erythrocytes.
用对绵羊红细胞抗体反应高（HA）和低（LA）的品系鸡进行了三项实验，以确定它们在用流产布鲁氏菌进行初次免疫后的抗体反应。在实验1中，HA品系鸡在免疫后7天的免疫反应中总滴度高于LA品系鸡。在免疫后5天和7天，HA品系鸡中抗2-巯基乙醇（IgG）滴度均高于LA品系鸡。在第一项实验的第7天也存在显著的性别效应，雄性的总滴度高于雌性。在第二项实验中，HA品系鸡在免疫后5天的总滴度高于LA品系鸡，但两个品系的IgG滴度相似。在实验3中使用的HA品系鸡在免疫后5天和7天的总滴度和IgG滴度均显著高于LA品系鸡。尽管HA和LA品系鸡最初是根据对绵羊红细胞的抗体反应性进行选择的，但它们对流产布鲁氏菌均表现出不同的抗体反应。
