Girard J P, Fernandes B
Schweiz Med Wochenschr. 1975 Sep 13;105(37):1174-9.
Using the various markers of human lymphocytes, it is possible to define, at least roughly, some malignancies of the lymphoid system in terms of their components in T and B cell subpopulations. Furthermore, the study of surface-immune globulins using labelled antisera specific for heavy and light chain classes, has made it possible to define the concept of monoclonal proliferation of B cells. Following a short description of the various interrelationships between B and T lymphocytes, the main lymphoproliferative diseases are briefly described in terms of B or T nature of tumoral cell lines and their bearing on the overall function of the immune apparatus.
利用人类淋巴细胞的各种标志物,至少大致可以根据其在T和B细胞亚群中的组成来界定淋巴系统的某些恶性肿瘤。此外,使用针对重链和轻链类别的标记抗血清对表面免疫球蛋白进行研究,使得定义B细胞单克隆增殖的概念成为可能。在简要描述了B淋巴细胞和T淋巴细胞之间的各种相互关系之后,将根据肿瘤细胞系的B或T性质及其对免疫器官整体功能的影响,简要描述主要的淋巴增殖性疾病。