大鼠胃肠道肽和细胞增殖的昼夜变化：肾上腺切除术的影响。
Circadian variations of gastrointestinal peptides and cell proliferation in rats: effects of adrenalectomy.
作者信息
Pasley J N, Burns E R, Rayford P L
机构信息
Department of Physiology, Biophysics, and Anatomy, University of Arkansas for Medical Sciences, Little Rock 72205.
出版信息
Recent Prog Horm Res. 1994;49:359-65. doi: 10.1016/b978-0-12-571149-4.50025-8.
The hypothalamo-pituitary-adrenal axis appears to play an important role in regulating the circadian fluctuations of brain-gut peptides, as well as the cell cycle of the gastrointestinal mucosa. Since dexamethasone treatment tended to restore circadian fluctuations lost to adren-x, the influence of adrenal glucocorticoids in the coordination of the rhythms of regulatory peptides and cell cycle kinetics appears to be substantial.
下丘脑-垂体-肾上腺轴似乎在调节脑肠肽的昼夜波动以及胃肠道黏膜的细胞周期中发挥重要作用。由于地塞米松治疗倾向于恢复因肾上腺切除而丧失的昼夜波动，肾上腺糖皮质激素在调节肽节律和细胞周期动力学的协调方面的影响似乎很大。
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